Grand Rounds — Role of Circadian System in Regulation of Insulin Secretion: Implications for Diabetes Prevention and Treatment

Aleksey Matveyenko, Ph.D., presents Role of Circadian System in Regulation of Insulin Secretion: Implications for Diabetes Prevention and Treatment.

Grand Rounds — Evaluation of Diabetes Care Quality and Value: Role of Optum Labs in Patient-Centered Health Care Delivery Research

Rozalina G. McCoy, M.D., presents Evaluation of Diabetes Care Quality and Value: Role of Optum Labs in Patient-Centered Health Care Delivery Research.

Grand Rounds — Bedside to Bench and Back: Musculoskeletal Tissue Engineering

Michael J. Yaszemski, M.D., Ph.D., presents Bedside to Bench and Back: Musculoskeletal Tissue Engineering.

Using ultrasound elastography to quantify passive muscle stiffness in children: Effect of spasticity and botulinum toxin on muscle

Joline E. Brandenburg, M.D., Physical Medicine and Rehabilitation, discusses the rationale for studying passive muscle stiffness, the effects of spasticity on muscle in children with cerebral palsy.

Adipose-derived stem cell treatment for osteoarthritic knees

Jay Smith, M.D., describes a clinical trial to evaluate the safety and efficacy of adipose-derived mesenchymal stromal cell injections as a treatment for people with osteoarthritic knees.

Mayo Clinic researchers reduce inflammation in human cells, a major cause of frailty

Mayo Clinic researchers have discovered that targeting select pathways with JAK inhibitors reduced inflammation in human cells in culture dishes and decreased inflammation and frailty in aged mice.